Week 3 power rankings hinge on health and explosive defenses. Philadelphia remains No. 1, while Green Bay rockets into the top three behind Jordan Love’s clean reads and a revitalized run game with Josh Jacobs. Buffalo’s two-way punch keeps them dangerous, and San Francisco claws into the top five amid injury concerns, leaning on depth to grind out wins.

Fantasy angles center on Love’s efficiency, Jacobs’ workload, Micah Parsons’ expanding snap count, James Cook’s role in Buffalo, and Mac Jones stepping in for SF. Monitor matchups and injuries as these teams push toward October with playoff ambitions.

Detroit ran up 52 points against Chicago, with Amon-Ra St. Brown leading the way by pulling in three touchdowns and posting an elite 91.6 PFF offensive grade, underscoring his status as a weekly fantasy anchor. Rookie Isaac TeSlaa flashed again, snaring another highlight-reel grab and climbing to 17 snaps in Week 2, signaling a growing role on a high-powered offense.

Defensively, Brian Branch anchored the unit with a sack and a 91.4 grade, while Aidan Hutchinson pressed the edge at 80.8. The Lions’ line and playmakers created a strong floor for fantasy assets across the board, including Jameson Williams, Brock Wright, and Sam LaPorta, as Detroit looks to sustain this high-scoring output and climb in both standard and dynasty leagues.

Fantasy takeaway: TeSlaa’s uptick and St. Brown’s certainty keep Detroit’s passing game a top target stack, with deep-league appeal emerging from TeSlaa. IDP angles brighten for Branch and Hutchinson, while pass-catchers like Wright and LaPorta offer streaming upside in favorable matchups.

Drake Maye exploded in Week 2, earning 83.6 PFF and guiding New England to a 33-27 win with 101 yards and two deep TDs on 4-of-5 attempts over 10 yards. His growth hints at a plausible Year 2 breakout and a tasty late-round QB2 target for fantasy managers.

Green Bay’s defense overwhelmed Washington with 33 pressures and six sacks, illustrating how a fierce front can tilt games and fantasy days alike. Across the slate, Goff-to-St. Brown clicked for 115 yards and three TDs, while Browning shined under blitz for Cincinnati. Week 2 underscored the value of pressure, scheme, and big-play receivers in shaping fantasy outcomes.

Overall, Week 2 spotlighted breakout potential from young passers, elite defensive fronts driving scores, and the continued importance of game-script and play-caller creativity for fantasy rosters.

Baker Mayfield stitched a dramatic comeback for Tampa Bay, guiding a game-winning drive in the final minute after escaping Texans pressure on a crucial fourth down. A 15-yard cutback on Gardner-Johnson sealed the moment, cementing Mayfield’s late-game clutch in a 20-19 win at NRG Stadium. The night featured a competitive back-and-forth between Mayfield and Gardner-Johnson, with strategic pressure and improv highlights shaping the outcome.

Houston’s defense buzzed in the two-minute drill, but Mayfield’s poise and mobility kept the Buccaneers alive. Earlier exchanges and trash-talk framed a combustible rivalry, yet Mayfield’s finishing kick underscored his ability to manufacture a winning sequence when it matters most. Fantasy managers should note the Buccaneers’ tendency to lean on improvisation in tight games.